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Epidemic Listing

Year(s) / Region Area City or State / Disease

  • 1657 / Boston / Measles

  • 1687 / Boston / Measles

  • 1690 / New York / Yellow Fever

  • 1713 / Boston / Measles

  • 1729 / Boston / Measles

  • 1732-1733 / Worldwide / Influenza

  • 1738 / South Carolina / Smallpox

  • 1739-1740 / Boston / Measles

  • 1747 / Connecticut New York Pennsylvania South Carolina / Smallpox

  • 1759 / North America / Measles

  • 1761 / North America and West Indies / Influenza

  • 1772 / North America / Measles

  • 1775 / North America (especially in North East) / Unknown

  • 1775-1776 / Worldwide / Influenza

  • 1783 / Dover Delaware (was extremely fatal) / Bilious Disorder

  • 1788 / Philadelphia and New York / Measles

  • 1793 / Harrisburg PA (many unexplained deaths) / Unknown

  • 1793 / Middletown Pennsylvania (many mysterious deaths) / Unknown

  • 1793 / Philadelphia / Yellow Fever

  • 1793 / Vermont / (a "putrid" fever) and Influenza

  • 1793 / Virginia (killed 500 in 5 counties in 4 weeks) / Influenza

  • 1794 / Philadelphia Pennsylvania / Yellow Fever

  • 1796-1797 / Philadelphia Pennsylvania / Yellow Fever

  • 1798 / Philadelphia Pennsylvania (one of the worst) / Yellow Fever

  • 1803 / New York / Yellow Fever

  • 1820-1823 / Nationwide (started at Schuylkill River & spread) / Fever

  • 1831-1832 / Nationwide (brought in by English Immigrants) / Asiatic Cholera

  • 1832 / New York and other major cities / Cholera

  • 1833 / Columbus Ohio / Cholera

  • 1833-34 / Kentucky / Cholera

  • 1834 / New York City New York / Cholera

  • 1837 / Philadelphia / Typhus

  • 1841 / Nationwide (especially severe in the South) / Yellow Fever

  • 1847 / New Orleans / Yellow Fever

  • 1847-1848 / Worldwide / Influenza

  • 1848-1849 / North America / Cholera

  • 1849 / New York / Cholera

  • 1850 / Nationwide / Yellow Fever

  • 1850-1851 / North America / Influenza

  • 1851 / Coles County Illinois The Great Plains and Missouri / Cholera

  • 1852 / Nationwide (New Orleans 8 000 died that summer) / Yellow Fever

  • 1855 / Nationwide / Yellow Fever

  • 1857-1859 / Worldwide (one of the largest epidemics) / Influenza

  • 1860-1861 / Pennsylvania / Smallpox

  • 1865-1873 / Philadelphia New York Memphis Washington DC / A series of recurring epidemics of Smallpox Cholera Typhus Boston New Orleans Baltimore

  • 1873-1875 / North America & Europe / Influenza

  • 1878 / New Orleans (last great epidemic) / Yellow Fever

  • 1885 / Plymouth Pennsylvania / Typhoid

  • 1886 / Jacksonville Florida / Yellow Fever

  • 1918 / Worldwide (high point year) more people were hospitalized in WWI from this epidemic than wounds. US Army training camps became death camps with 80% death rate in some camps. / Influenza or Spanish Flu